Time equals money. Synthetic products offer the same durability achieved through lamination, but without the additional time and cost implications.
Take a 12×18” job, for example. You need 50 prints and it’s critically important that the output be tear-proof and resistant to moisture. You evaluate your options: either print using a synthetic substrate, or print using standard paper with a post-lamination process. While the synthetic substrate may carry a higher initial cost than the standard paper, there is no additional cost for lamination or labor. Bottom line, in this scenario: synthetics can be up to 35% more cost effective and reduce your turnaround time from hours to minutes.
Imagine the range of solutions with a substrate that is tear proof and completely resistant to moisture and grease. The availability of alcohol-resistant options is perfectly suited for environments where printed output is frequently reused and sanitized, like in hospitals and restaurants.